Edward Sylvester Ellis (April 11, 1840 - June 20, 1916) was an American author who was born in Ohio and died at Cliff Island, Maine.Ellis was a teacher, school administrator, journalist, and the author of hundreds of books and magazine articlesthat he produced by his name and by a number of noms de plume. Notable fiction stories by Ellis include The Steam Man of the Prairies and Seth Jones, or the Captives of the Frontier.Internationally, Edward S. Ellis is probably known best for his Deerfoot novels read widely by young boys until the 1950s Seth Jones was the most significant of early dime novels of publishers Beadle and Adams. During the mid-1880s, after a fiction-writing career of some thirty years, Ellis eventually began composing more serious works of biography, history, and persuasive writing. Of note was "The Life of Colonel David Crockett", which had the story of Davy Crockett giving a speech usually called "Not Yours To Give". It was a speech in opposition to awarding money to a Navy widow on the grounds that Congress had no Constitutional mandate to give charity. It was said to have been inspired by Crockett's meeting with a Horatio Bunce, a much quoted man in Libertarian circles, but one for whom historical evidence is non-existent. It is said that Seth Jones was one of Abraham Lincoln's favorite stories
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Neuron Glial 2 (NG2) cells are glial cells known to serve as oligodendrocyte progenitors as well as modulators of the neuronal network. Altered NG2 cell morphology and up-regulation as well as increased shedding of the proteoglycan NG2 expressed on the cell surface have been described in rodent models of brain injury. Here we describe alterations in the human NG2 cell population in response to pathological changes characteristic of Alzheimer's disease (AD). Our results demonstrate major alterations in the NG2 cell population in relation to AD pathology which highlights the NG2 cell population as a new attractive research target in the search for cellular mechanisms associated with AD pathogenesis. Proceeds from the sale of this book go to the support of an elderly disabled person.
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